Condition, treatment or phenotype | Number of genes responding to the treatments* | References |
---|---|---|
Phenotype screens of the deletion collection | Â | Â |
Fitness after growth on minimal medium, high salt, low salt, galactose, sorbitol, pH 8, heat shock, cold shock, or hydrogen peroxide | ? | [10] |
Growth on non-fermentable carbon substrates | 466 | [11] |
Response to DNA-damaging agents, ionizing radiation, UV radiation, cisplatin, or hydrogen peroxide | >170 | [13-16] |
Chemical DNA damage (methane sulfonate sensitivity) | 103 | [17] |
Enhanced sporulation proficiency | 102 | [18,19] |
Sporulation defects | 261 | [18,19] |
Post-germination defects | 158 | [18,19] |
Genes essential for sporulation | 334 | [18,19] |
Saline response | About 500 | [12] |
Suppression of the accumulation of mutations | 33 | [20] |
Non-homologous DNA end-joining | About 30 | [21] |
Ty1 retrotransposition cycle | 101 | [22] |
Response to the introduction of human Huntingtin or α-synuclein fragments (unfolded protein response) | 52/86 | [23] |
Karmellae assembly | 120 | [24] |
Bipolar bud-site selection | 127 | [25] |
Cell-size distribution | 500 | [26,27] |
Altered cell morphology | ? | [28] |
Meiotic chromosomal segregation | ? | [29] |
Vacuolar protein sorting | 146 | [30] |
Host genes affecting replication of a positive-strand RNA virus | 100 | [31] |
Glycogen storage (low, high) | 324, 242 | [32] |
Sensitivity of the deletion collection to drugs or chemicals | Â | Â |
Rapamycin | 106 | [43] |
PS-341 | ? | [38] |
Bleomycin (hypersensitivity, resistance) | 231, 5 | [37,40] |
Amoxillin, penicillin, rifampin, vancomycin, (oxy)tetracycline, or gentamicin | 23 | [42] |
Anticancer, antifungal agents, statins, alverine citrate, dyclonine, or nystatin | About 10 | [10,41] |
K1 killer toxin, hygromycin B, calcofluor or sodium dodecyl sulfate | 268 | [44] |
6-Azauracil | 42 | [45] |
Wortmannin (resistance, sensitivity) | 591, 476 | [39] |
Phenotypes of transposon-insertion libraries | Â | Â |
Phenotypes under 20 conditions, expression levels and subcellular localization (TRIPLES database) | ? | [55] |
High salt | 31 | [58] |
Survival of hypo-osmotic shock and growth at 15°C | 10 | [58] |
Ethanol tolerance and cell-wall modifications | 5 | [59] |
Nitrogen starvation, invasive or filamentous growth and sporulation | About 105 | [60] |