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Figure 6 | Genome Biology

Figure 6

From: MONKEY: identifying conserved transcription-factor binding sites in multiple alignments using a binding site-specific evolutionary model

Figure 6

The evolutionary distance required to confidently identify conserved binding sites varies among transcription factors. (a) Median p-values for functional binding sites for various factors at different evolutionary distances. The evolutionary distance needed to obtain a desired significance varies between factors. (b) Predicted dependence of the p-values on evolutionary distance. Specificity data and functional binding sites were obtained from the SCPD.

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Genome Biology

ISSN: 1474-760X

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