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Table 2 Conservation properties of module core components for those functional networks with more than one statistically significant module core

From: How biologically relevant are interaction-based modules in protein networks?

 

Conservation

Function

(B,A,E)

(-,-,E)

Cell fate

0(0)

6(3)

Metabolism

3(1)

6(3)

Cellular organization

3(0)

6(3)

Cellular environment

3(2)

1(1)

Protein synthesis

3(0)

2(2)

Transcription

1(1)

8(3)

Cell cycle

0(0)

7(2)

  1. Conservation of components follows two distinct patterns: module core components are conserved in all three kingdoms: (B,A,E) Bacteria, Archaea and Eukarya, or are only present in eukaryotes, (-,-,E). The table shows the number of module cores, with branch length ξ m ≥ 0.1, whose components have a representative phylogenetic profile of either type. Conservation profiles of statistically significant core components is shown in parenthesis. See also Table 1.
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Genome Biology

ISSN: 1474-760X

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