Figure 2From: Feminizing chicks: a model for avian sex determination based on titration of Hint enzyme activity and the predicted structure of an Asw-Hint heterodimerHint hydrolases are not cooperative for AMP-NH2 hydrolysis. Substrate concentration-dependent hydrolytic rates (per monomer) for rabbit Hint (filled circles) and yeast Hnt1 (open triangles) indicate that Hint hydrolases, although dimeric, have a single Km for substrate. Reproduced with permission from [30].Back to article page