Open Access

Articles selected by Faculty of 1000: Fat regulation in C. elegans; disease gene identification; comparision of mouse and human genomes; C. elegans early embryonic transcriptome; functional genomics in C. elegans

  • The Author(s)
Genome Biology20034:311

DOI: 10.1186/gb-2003-4-3-311

Published: 14 February 2003

Summary

A selection of evaluations from Faculty of 1000 covering several post-genomic studies in C. elegans, the use of 'integrative genomics' in disease gene identification and a comparison of mouse and human genomes.

Fat regulation in C. elegans

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. Nature 2003, 421:268-272.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Ashrafi

Disease gene identification

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics. Mootha VK, Lepage P, Miller K, Bunkenborg J, Reich M, Hjerrild M, Delmonte T, Villeneuve A, Sladek R, Xu F, et al. Proc Natl Acad Sci U S A 2003, 100:605-610.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Mootha

Comparision of mouse and human genomes

Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes. Guigo R, Dermitzakis ET, Agarwal P, Ponting CP, Parra G, Reymond A, Abril JF, Keibler E, Lyle R, Ucla C, et al. Proc Natl Acad Sci U S A 2003, 100:1140-1145.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Guigo

C. elegans early embryonic transcriptome

Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. Baugh LR, Hill AA, Slonim DK, Brown EL, Hunter CP. Development 2003, 130:889-900.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Baugh

Functional genomics in C. elegans

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M, Kanapin A, Le Bot N, Moreno S, Sohrmann M, et al. Nature 2003 421:231-237.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Kamath

Copyright

© BioMed Central Ltd 2003