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Figure 1 | Genome Biology

Figure 1

From: Comparing cDNA and oligonucleotide array data: concordance of gene expression across platforms for the NCI-60 cancer cells

Figure 1

Histograms showing the distribution of correlation coefficients for UniGene-matched and UniGene-mismatched transcripts. Pearson correlation coefficients for (a) cDNA-array and oligoarray transcript pairs that map to the same UniGene cluster and for (b) pairs that map to different UniGene clusters. (c) Modeling of the correlation distribution in (a) in terms of a component (22%) based on (b) representing mistaken matchings and a component (78%) based on true matches. This was an eye-fit of the one parameter representing the proportions of the two populations of values. (d) The same as in (a) but with Spearman (non-parametric) correlation coefficients. (e) The same as in (b) but with Spearman correlation coefficients. (f) Distribution of Pearson correlations for UniGene-matched cDNA-oligo transcripts that have not been sequence-verified. (g) The same as in (e) but for sequence-verified transcripts.

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Genome Biology

ISSN: 1474-760X

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