Skip to main content
Figure 1 | Genome Biology

Figure 1

From: Profound effect of normalization on detection of differentially expressed genes in oligonucleotide microarray data analysis

Figure 1

Pre- and post-normalization signal intensity scatterplots. The x-axis in all panels except (c) represents the not normalized average difference values (AD) derived from the Affymetrix GeneChip software after scanning. (a) y-axis is invariant-feature normalization with calculation of AD values. (b) y-axis is invariant-feature normalization with model-based expression values (MBEV). (c) x-axis is invariant-feature normalization with calculation of AD values; y-axis is invariant-feature normalization with MBEV. (d) y-axis is invariant probe set normalization. (e) y-axis is global scaling. Blue dots, subA-array; pink dots, subB-array.

Back to article page