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Figure 1 | Genome Biology

Figure 1

From: Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands

Figure 1

An example multiple sequence alignment of seven receptors. Protein sequences of GPR87, KI01, GPR86, P2Y12, H963, GPR34 and PAFR belonging to subgroup 12 were aligned with ClustalX and modified by deleting the extremely variable amino termini upstream of the first transmembrane domain and carboxyl termini downstream of the seventh transmembrane domain as indicated. Identical amino-acid residues in all aligned sequences are shaded in black and similar residues in gray. Transmembrane (TM) domains identified by the TMpred program are indicated.

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Genome Biology

ISSN: 1474-760X

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