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Table 1 Summary of the 29 new genes

From: Prediction of unidentified human genes on the basis of sequence similarity to novel cDNAs from cynomolgus monkey brain

Monkey accession number

Cynomolgus monkey (Macaca) clone

Location*

RT-PCR†

Length (amino acids) in Macaca‡

Length (amino acids) in human§

Number of exons¶

Exon predicted#

Functional annotation (putative)**

AB055251

QflA-10072

10p12.1

+

743

743

2 (1)

1 (0)

Adenylate kinase

AB055256

QflA-10350

9q34.3

-

308

276

5 (4)

1 (1)

Unknown

AB055264

QflA-10778

2q24.2

-

603

577

13 (13)

6 (2)

Nuclear protein

AB056798

QflA-11110

6q23.2

+

621

617

5 (5)

3 (0)

Sugar transporter

AB055271

QflA-11149

1p31.1

-

510

514

5 (4)

2 (0)

Leucine-rich repeat protein

AB055273

QflA-11186

10q26.2

+

624

625

8 (8)

4 (1)

Unknown

AB055276

QflA-11332

17q23.3

+

590

590

17 (14)

10 (1)

Unknown

AB055278

QflA-11381

11q22.3

+

197

197

1 (1)

0 (1)

Unknown

AB055280

QflA-11470

7q11.22

-

114

114

1 (1)

0 (0)

Unknown

AB056389

QflA-12365

10q26.3

++

368

369

12 (10)

6 (2)

Serine/threonine protein kinase

AB055295

QflA-12453

5q35.2

-

103

103

2 (1)

0 (0)

Unknown

AB056800

QflA-12512

15q15.2

+

653

653

20 (16)

10 (2)

Glycoside hydrolase family 31

AB056802

QflA-12743

7q11.21

++

214

214

6 (4)

2 (2)

Unknown

AB060227

QflA-15038

9q34.13

+

327

327

2 (2)

1 (1)

Unknown

AB056812

QflA-15102

4p15.1

+

102

102

1 (1)

0 (0)

Unknown

AB060245

QflA-15249††

11p15.1

+

413

369

11 (9)

8 (1)

Thyrosine phosphatase

AB056426

QflA-15366

10q22.1

+

581

581

3 (2)

2 (0)

Cysteine-rich protein with leucine-rich repeat

AB066513

QmoA-10247

1q25.3

+

196

196

11 (6)

1 (1)

G-protein signaling protein

AB063014

QmoA-11221

6q14.1

-

430

430

7 (6)

4 (2)

Nuclear protein

AB063019

QmoA-11380

Xq13.3

+

309

309

7 (1)

0 (0)

Unknown

AB063029

QmoA-11613

10p12.33

++

654

654

12 (11)

5 (2)

Unknown

AB066529

QmoA-11640

16p12.3

-

122

122

2 (1)

0 (0)

Unknown

AB066540

QmoA-12446

19q13.2

-

654

655

3 (3)

0 (1)

Zinc-finger protein with KRAB domain

AB066542

QmoA-12482

10p11.23

+

391

392

5 (2)

1 (1)

Zinc-finger protein

AB063089

QtrA-10552

11q22.3

+

664

664

16 (12)

9 (2)

RNA-binding methyl transferase

AB060878

QtrA-12612

9q32

+

238

238

5 (3)

2 (1)

Nuclear protein

AB063095

QtrA-13256

6q27

+

300

301

18 (12)

9 (0)

Unknown

AB060262

QtrA-14732

3p21.31

++

396

396

3 (3)

3 (3)

Unknown

AB060922

QtrA-14779††

1p31.1

+

432

536

12 (11)

6 (1)

Adenylate kinase

  1. *Human chromosomal locationwas determined by computer homology search of the human genome working draft sequence at UCSC. †Results of RT-PCR analysis: +, single product; ++, multiple products; -, no product. QtrA-10552 and QtrA-13256 showed a distinct splicing pattern between human and Macaca. ‡Length of putative coding region deduced from cDNA sequence of Macaca. §Length of putative coding region deduced from human genome sequence corresponding to cDNA of Macaca. ¶Number of exons in the human hypothetical cDNA. The number of coding exons is in parentheses. #Number of exons correctly predicted by GenScan in the human genome. Partially predicted exons are in parentheses. **Function of putative protein was deduced by InterPro category search and BLAST homology search. ††ORF sequence was revised by sequencing the RT-PCR product.
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Genome Biology

ISSN: 1474-760X

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