Figure 1
From: New clues to the puzzle of mammalian sex determination
Proposed interactions among transcription factors during mammalian male sex determination and gonadal development (for further details, see text). Arrowed lines represent activation; blunt-ended lines represent repression. The unequal size of the boxes around the WT1 isoforms represents the observation that the total amount of WT1 remains constant and that WT1+KTS is normally the predominant WT1 isoform.