Figure 2From: Structure and dynamics of the post-transcriptional mRNA-processing machinerySubcellular localization of the Ref protein REF2-II in HeLa cells. REF2-II is distributed at lower levels throughout the nucleoplasm and is concentrated in 20-40 distinct domains, called the nuclear speckles, which are nuclear sub-compartments enriched in splicing factors. Two identical cells are shown.Back to article page